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  3. 1 draw the binding curve of protein a and b...

Question: 1 draw the binding curve of protein a and b...

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1. Draw the binding curve of protein A and B, based on the following description if the curve shape and the Ke value are drawn unclear (4 pts), No credit will be givern Protein (A) is a dimer in quaternary structure and has a ligand (L) The subunit (a) in protein A increases its binding affinity to (L) when the subunit (a) binds to (L) A dissociation constant (K,) between protein A and a ligand (L) is 1 M Protein A a 0 12 3 4 56 [L] Protein (B) is a dimer in quaternary structure and has a ligand (M) The subunit (B) in protein B does not change its binding affinity to (M) when the subunit (3) binds to (M) A dissociation constant (Ka) between protein B and a ligand (M) is 2 M. Protein 8 0 1 2 345 6 [M]
2 Assume that oxygen concentrations in lung and tissue are 100 and 20 torr, respectively. Draw the O binding curve of hemoglobin that shows the 80% delivery of oxygen between lung and tissue. No ooit war be given if the curve shape and the delivery amount are drawn unclear (2 pts) 0.8 0.6 0.4 0.2 0 0 20 40 60 80 100 120 torr O2 З. There is one enzyme (E) You evaluated two compounds (A and B) for their rates o, reactions with enzyme E. Below are the values of initial rates depending on substrate concentration 2ot determine the Knand Kan values of both compounds (A and B). The total enzyme concentration used is 10 nM. Determine which one (A or B) has higher catalytic efficiency. Use Excel program, (4 pts) 0 020 0.038 O 057 007 015 0027 0.045 0 058 0083 0.067 0074 0105 0087 10 091 0095 0.104
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