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Question: 1 duloxetine was approved for pain relief in osteoarthritis in...

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1.         Duloxetine was approved for pain relief in osteoarthritis in 2010. Find a study that supports this approval and comment on how convincing you find it to be.

2.         A 55 yo female patient with severe osteoarthritis of the knee is dispensed a prescription for 50 tabs of hydrocodone 7.5 mg/acetaminophen 325 mg to be used as 1 or 2 tabs every 6 hours as needed. After two weeks, the patient is back for the same prescription, and once again in another two weeks.

a. What could be the reasons for the frequent prescriptions?

b. What actions would you take with the patient and prescriber at this point? Explain your reasoning.

3.         a. Would you recommend glucosamine to your OA patients? Explain why.

            b. Would you recommend vitamin D supplements? What evidence is there?

4.         Evaluate the efficacy and safety of ONE of the following dietary supplements or alternative treatments for osteoarthritis: MSM, SAMe, turmeric, or acupuncture.  

                                   

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