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48 chloramphenicol is an antibiotic that binds the bacterial 70s...

Question: 48 chloramphenicol is an antibiotic that binds the bacterial 70s...

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48) Chloramphenicol is an antibiotic that binds the bacterial 70S ribosomal subunit, exploiting differences in that leave the 80S eukaryotic ribosomal subunit alone. Although very effective at inhibiting prote -threateni structure synthesis, and once widely used, today chloramphenicol is only rarely used clinically (e g, in life circumstances) due to its toxicity in humans, that was not originally realized. What structure(s) in ou you think chloramphenicol is targetting, leading to this toxicity? Hint: this is not an allergic reaction (which would involve an immune response). Please propose a structure/process and explain.

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