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Question: a why does fetal hemoglobin have a higher affinity for...

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PyMOL> EALERMFLSFPTTKTYF PHFDLSHGSAOVKGHGKKVADAL TNAVAHVOLMPNAL LSDLHAHKLRUDPUNFKL LVTLAAHLPAEFTPAYHASLDKFLASVSTULTSKYR (selc> No License Fi1c For Evaluation Only 30 days remaining use Mode 3-Button Viewin & Keys Rota Mowe MovZ Slab Ctrl Move PkAt Pk1 MvS Buttons L R Whee ente Beta_Subunits front Coordinating Residues Alpha chain coordination residues Al pha-Chai ns-Only Residues Onlu x Box Elip MouS Ctsh Sele Orig Clip Movz nglCLk Cent Menu PkAt Db1CIk Menu Selecting Residues

A. Why does fetal hemoglobin have a higher affinity for O2 than adult hemoglobin?

B. Residues H2, K82, and H143 of both b1 and b2 in adult hemoglobin play a role in 2,3-bisphosphoglycerate binding. What are the corresponding residues in fetal hemoglobin?

C. What does this do to the binding site in fetal hemoglobin?

---Download the PyMOL file 1FDH to investigate this difference. (The picture above is the downloaded picture. Please help me out with this question. Please explain them in detail. )

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