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Item 4 Review The figure below illustrates enzyme activities as fúnctions of temperature and pH. In general, the activity of a specific enzyme is highest at the temperature and pH that are characteristic of the environment in which the enzyme normally functions. Optimal temperature for a typical human enzyme Optimal temperature for atypical enzyme of thermophilic (heat-tolerant) bacteria 20 40 60 80 100 TemperatureC) pH optimum for trypsin $ PH optimum for pepsin 0 1 2 3 4 5 6 7 89 10 pH FIGURE The Effect of Temperature and pH on the Reaction Rate of Enzyme-Catalyzed Reactions. Every enzyme has an optimum temperature and pH that usually reflect the environment where that enzyme is found in nature.
Part A Explain the shapes of the curves in the figure in terms of the major chemical or physical factors that affect enzyme activity Select all that apply. The pH optimum for an enzyme corresponds to the proton concentration at which ionizable groups on the enzyme and the substrate molecules U are in the most favorable form for chemical reactivity As the temperature is raised above the optimum of the enzyme, it undergoes thermal denaturation. 3 The ph optimum for an enzgyme corresponds to the proton concentration at which onizable groups on the enzyme and the substrate molecaules are the most ionized Reaction veloity increases above the tomperature which corresponds to the optimum of the enzyme. This is consistent with the effect of The reaction velocity increases steadily as the temperature is increased from a colder temperature to the temperature optimum of the enzyme, consistent with the effect of temperature on chemical reactions in general Each enzyme has a temperature optimum that is at or near the temperature of the organism.
For each enzyme in the figure, suggest the adaptive advantage of having the enzyme activity profile shown in the figure Select all that apply. Both enzymes are maximally active at or near the temperature of the milleu in wirigh they are found. Both enzymes are maximally active at high temperatures. Both enzymes are maximally active at or near the pH of the neutral solution. Both enzymes are maximally active at or near the pH of the milieu in which they are found. Submit
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