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  3. c drug a is readily absorbed from the gastrointestinal tract...

Question: c drug a is readily absorbed from the gastrointestinal tract...

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(c) Drug A is readily absorbed from the gastrointestinal tract by passive diffusion. Predict the most likely effect of each of the structural changes on the absorption of the resulting analogues of A in the intestines, assuming that each of the analogues is still absorbed by passive diffusion; i. Incorporating a carboxylic acid group into the structure of A ii. Incorporating an amino group into the structure of A, ii. Esterfying an existing carboxylic acid group in the structure of A iv. Incorporating a sulphonate group into the structure of A.

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