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Question: chapter 16 problem 30 it makes metabolic sense for acetylcoa...

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Chapter 16, Problem 30 It makes metabolic sense for acetyl-CoA, which is not a substrate for gluconeogenesis, to activate pyruvate carboxylase because a high level of acetyl-CoA, the product of catabolism (it is also generated from and catabolism), indicates that the cell has adequate metabolic fuel available. The stimulation of pyruvate carboxylase, the first enzyme of gluconcogenesis, allows the cell to direct resources toward glucose synthesis, a mechanism for stockpiling fuel for later use.

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