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Question: cystic fibrosis cf is caused by a genetic mutation resulting...

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Cystic fibrosis (CF) is caused by a genetic mutation resulting indefective proteins in secretory cells, mainly in the epithelial lining ofthe respiratory tract. The one in every 2,000 Caucasian babies who hasthe disease is homozygous for the recessive mutant. Although medical treatment is becoming more effective, in the past, most children with CF died before their teens. About 20 Caucasians in 2,000 are carriers of the trait, having one mutant and one normal allele, but they do not develop the disease. According to rules of population genetics, the frequincy of the homozygous recessive genotype should be rarer than it is. What is one possible explanation for the unusually high frequency of this allele in Caucasian populations?

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