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3. hi zookal i have narrow down the question to here...

# Question: hi zookal i have narrow down the question to here...

###### Question details

HI Zookal,

I have narrow down the question to here ...Could you pls just look at the OR and CI  results from artcle and what thsi means to  Intention-to-treat analysis? Adequacy of sample size ? can you explain below green color for me, that will be great.

·         OR 2.4 (>1), 95% CI 1.2-4.6 (wide), p=0.010 (P<.05 means significant). This indicates ???

·         Participants in the intervention group had a better score on the physical component of the 12-item short form health survey at 6-months to the comparison group; difference = 1.75, 95% CI 0.21- 3.28, p=0·026 (P<.05 means significant). This indicates ???

• Smoking cessation at 12 months after randomisation.
• Number of cigarettes smoked per day at 6 and 12 months
• Fagerstrom Test for Nicotine Dependence and Motivation to Quit results at 6 and 12 months.

Based on the validity of the study and strength of the results,

Could you find anyone good at reseacrh or Statistical analysis, pls help me interpret the result of the table below,   the article from

Gilbody, S. (2019). Smoking cessation for people with severe mental illness (SCIMITAR+): a pragmatic randomised controlled trial. Lancet Psychiatry, 6, 370-390. doi:10.1016/S2215-0366(19)30047-1

o    Allocation concealment ??

o    All participants accounted for at the time of data analysis?

o    Intention-to-treat analysis?

o    Provide an overall summary judgement statement of the validity based on your appraisal.

Present and discuss the following study results and outcome measures, including interpretation of the effect size, the precision of the effect size and statistical significance:

• Smoking cessation at 12 months after randomisation.
• Number of cigarettes smoked per day at 6 and 12 months
• Fagerstrom Test for Nicotine Dependence and Motivation to Quit results at 6 and 12 months.

Based on the validity of the study and strength of the results, discuss the possible application of the evidence to the scenario provided here -your service has a very successful program to support clients to stop smoking. The directors of the service wish to extend this smoking cessation program to clients with mental illness, but are unsure of the best methods to support these clients. Your manager has asked you to investigate smoking cessation programs for clients with mental illness. You start by performing a literature search and find the following article:

"Smoking cessation for people with severe mental illness (SCIMITAR+): a pragmatic randomised controlled trial." Gilbody et al. 2019.  The Lancet Psychiatry 6(5): 379-390.