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In Chapter 10, we will be learning about a chemically-gated CATION channel which lets both Na+ and K+ ions through. Use your knowledge to consider the following about an open CATION channel Will Na+ diffuse into or out of the cell? Will K+ diffuse into or out of the cell? Which will diffuse faster? The second factor that influences the permeability of the cell is the number of leak channels present in the cell membrane. Most IN or OUT IN or OUT Na+ or cells have more potassium leak channels Which of the following is true about cell permeability as a whole (multiple channels in the cell membrane)? A) B) C) D) Na+ is more permeable to the cell membrane because there are more Na+ leak channels Na+ is more permeable to the cell membrane because there are less Na+ leak channels K+ is more permeable to the cell membrane because there are more K+ leak channels K+ is more permeable to the cell membrane because there are less K+ leak channels The pigment melanin is produced in specialized skin cells called melanocytes. Melanocytes store pigment in specialized secretory vesicles called melanosomes. These vesicles are membrane-bound organelles. While melanocytes make melanin, there are relatively few numbers of melanocytes in our integument. Our skin color is more influenced from melanocytes transferring the contents of the melanosome into the nearby, more numerous, keratinocytes. Once transferred, keratinocytes will store the melanin around their nucleus; helping protecting our DNA from sun damage. Melanin remains in keratinocytes until they slough off the integument as dead skin Mark all of the following statements that are true; derived from the above reading, your base knowledge, book info and corresponding ppt slide Melanosomes have a phospholipid bilayer Skin would be significantly less pigmented without melanocytes Melanin is the only contribution to skin color Adaptedfrom Curr Opin CeliBicl 2014 Asgust: 01- Melanocyte -Melanocytes are the most numerous cell type -Melatonin is a pigment Melanin Petin Cells must be alive for melanin transfer to occur The mechanism of transfer of melanin out of a melanocyte is C) D) E) F) Exocytosis Passive Transport Both A& B None of the above A) Endocytosis B) Phagocytosis The mechanism of transfer of melanin out of a keratinocyte is A) Endocytosis B) Phagocytosis C) Exocytosis D) Passive Transport E) Both A& B F) None of the abovePlease answer. Thank you so much!

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