Question: question 1 you are a cancer researcher studying skin cancer...
You are a cancer researcher studying skin cancer cells that have become metastatic (i.e.
they’ve migrated from the site of the original tumor to establish new secondary tumors). You
analyze skin samples from an unaffected patient and from one with the metastatic cancer. After
a series of detergent solublization and centrifugation steps, you separate pellet samples from
each tissue type by gel electrophoresis and find the following results:
A. What is the difference between the normal skin sample versus the skin cancer tissue
sample? (2 points)
B. Which protein would you select for further study? (2 points)
C. Many proteins work in complexes with other proteins. How could you determine if the cancer
protein in question above has one or more intracellular binding partners? (6 points)