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Question: the nicotinic acetylcholine receptor is a cation channel in the...

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The nicotinic acetylcholine receptor is a cation channel in the plasma membrane of some neurons. It is composed of five subunits, each of which is a transmembrane protein. The hydropathy plot of one of the subunit is shown. How many membrane-spanning alpha helices do you predict for this protein subunit? The hydropathy index shows DeltaG (hydrophobic --> water).

The plasma membrane of a neuron is 3.5 nm thick.

4 2 0 2 2-2 300 400 200 Amino acid 100

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